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doi: 10.3389/fimmu.2021.673708

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However, an optimal gene copy number should be considered because of metabolic burden by protein overexpression ( sod -lc gene expression were constructed under promoter #14 (Figure 3A), which one to four copy number recombinants named as S-3/pKLH167, S-3/pKLH337, S-3/pKLH341, and S-3/pKLH344